POLR3K Antikörper

Produktnummer ABIN7117684

Produktdetails anti-POLR3K Antikörper

Target: POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR3K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: polymerase(RNA) III(DNA directed) polypeptide K, 12.3 kDa

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu POLR3K

Target: POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))

Andere Bezeichnung: POLR3K (POLR3K Produkte)

Synonyme: MGC108467 antikoerper, POLR3K antikoerper, 12.3kDa antikoerper, 1500004O14Rik antikoerper, AI196849 antikoerper, AU014893 antikoerper, C11 antikoerper, RPC10 antikoerper, RPC11 antikoerper, C11-RNP3 antikoerper, RPC12.5 antikoerper, hRPC11 antikoerper, RNA polymerase III subunit K antikoerper, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa S homeolog antikoerper, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa antikoerper, polymerase (RNA) III (DNA directed) polypeptide K antikoerper, Polr3k antikoerper, polr3k.S antikoerper, polr3k antikoerper, POLR3K antikoerper

Hintergrund: Synonyms:C11, C11 RNP3, hRPC11, HsC11p, My010, POLR3K, RNA polymerase III subunit C10, RNA polymerase III subunit C11, RPC10, RPC11, RPC12.5 Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs(EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).

Molekulargewicht: 12 kDa

Gen-ID: 51728

UniProt: Q9Y2Y1