Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PSME4 Antikörper

PSME4 Reaktivität: Human, Maus, Ratte WB, ELISA, IP, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7117899
  • Target Alle PSME4 Antikörper anzeigen
    PSME4 (Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 8
    Kaninchen
    Klonalität
    • 8
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    Dieser PSME4 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    proteasome(prosome, macropain) activator subunit 4
    Isotyp
    IgG
    Top Product
    Discover our top product PSME4 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IP: 1:500-1:1000 , IHC: 1:50-1:500, IF: 1:10-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    PSME4 (Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))
    Andere Bezeichnung
    PSME4 (PSME4 Produkte)
    Synonyme
    proteasome activating protein 200 antikoerper, Afu4g11290 antikoerper, An04g05320 antikoerper, AO090003001091 antikoerper, PA200 antikoerper, AA409398 antikoerper, AU041366 antikoerper, TEMO antikoerper, mKIAA0077 antikoerper, proteasome activator subunit 4 antikoerper, proteasome activating protein 200 antikoerper, proteasome (prosome, macropain) activator subunit 4 antikoerper, PSME4 antikoerper, Psme4 antikoerper, PA200 antikoerper, AFUA_4G11290 antikoerper, ANI_1_888184 antikoerper, AOR_1_1944154 antikoerper, TERG_07227 antikoerper, psme4 antikoerper
    Hintergrund
    Synonyms:KIAA0077 Background:Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP-and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like(BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Component of the spermatoproteasome, a form of the proteasome specifically found in testis: binds to acetylated histones and promotes degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. Also involved in DNA damage response in somatic cells, by promoting degradation of histones following DNA double-strand breaks.
    Molekulargewicht
    140 kDa
    Gen-ID
    23198
    UniProt
    Q14997
    Pathways
    DNA Replication, Synthesis of DNA
Sie sind hier:
Kundenservice