RAB7B Antikörper

Produktnummer ABIN7118233

Produktdetails anti-RAB7B Antikörper

Target: RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB7B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: RAB7B, member RAS oncogene family

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu RAB7B

Target: RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Andere Bezeichnung: RAB7B (RAB7B Produkte)

Synonyme: RGD1562617 antikoerper, RAB7B antikoerper, RAB7 antikoerper, Rab7b antikoerper, Rab7b, member RAS oncogene family antikoerper, rab7B protein antikoerper, RAB7B, member RAS oncogene family antikoerper, RAB7B, member RAS oncogene family S homeolog antikoerper, Rab7b antikoerper, rab7B antikoerper, RAB7B antikoerper, rab7b.S antikoerper, rab7b antikoerper

Hintergrund: Synonyms:Ras-related protein Rab-7b, RAB7B Background:Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF-and EGFR degradation pathway.

Molekulargewicht: 23 kDa

Gen-ID: 338382

UniProt: Q96AH8