RSAD2 Antikörper
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- Target Alle RSAD2 Antikörper anzeigen
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RSAD2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- radical S-adenosyl methionine domain containing 2
- Isotyp
- IgG
- Top Product
- Discover our top product RSAD2 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
- Andere Bezeichnung
- RSAD2 (RSAD2 Produkte)
- Synonyme
- CIG6 antikoerper, RSAD2 antikoerper, 2510004L01Rik antikoerper, cig33 antikoerper, cig5 antikoerper, vig1 antikoerper, Vig1 antikoerper, Best5 antikoerper, si:ch211-276e8.2 antikoerper, zgc:112342 antikoerper, viperin antikoerper, rsad2 antikoerper, radical S-adenosyl methionine domain containing 2 antikoerper, viperin antikoerper, RSAD2 antikoerper, Rsad2 antikoerper, rsad2 antikoerper, vig1 antikoerper
- Hintergrund
- Synonyms:2510004L01Rik, cig33, cig5, RSAD2, vig1, Viperin Background:Interferon-inducible iron-sulfur(4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus(HCMV), hepatitis C virus(HCV), west Nile virus(WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus(VSV), and human immunodeficiency virus(HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase(FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells(pDCs) by facilitating Lys-63'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor(TCR)-mediated GATA3 activation and optimal T-helper 2(Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.
- Molekulargewicht
- 45 kDa
- Gen-ID
- 91543
- UniProt
- Q8WXG1
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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