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TRIM27 Antikörper

TRIM27 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7118412
  • Target Alle TRIM27 Antikörper anzeigen
    TRIM27 (Tripartite Motif Containing 27 (TRIM27))
    Reaktivität
    • 40
    • 20
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 38
    • 2
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TRIM27 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 14
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    tripartite motif-containing 27
    Isotyp
    IgG
    Top Product
    Discover our top product TRIM27 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IP: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    TRIM27 (Tripartite Motif Containing 27 (TRIM27))
    Andere Bezeichnung
    TRIM27 (TRIM27 Produkte)
    Synonyme
    RFP antikoerper, RNF76 antikoerper, AW538890 antikoerper, Gm19403 antikoerper, Rfp antikoerper, TRIM27 antikoerper, Rfp1 antikoerper, tripartite motif containing 27 antikoerper, tripartite motif-containing 27 antikoerper, TRIM27 antikoerper, Trim27 antikoerper
    Hintergrund
    Synonyms:Ret finger protein, RFP, RING finger protein 76, RNF76, TRIM27, tripartite motif containing 27, Zinc finger protein RFP Background:E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity, mediates the formation of 'Lys-48'-linked polyubiquitin chains, the function inhibits CD4 T-cell activation. Acts as a regulator of retrograde transport: together with MAGEL2, mediates the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASH1, leading to promote endosomal F-actin assembly(PubMed:23452853). Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double-stranded DNA.
    Molekulargewicht
    58 kDa
    Gen-ID
    5987
    UniProt
    P14373
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