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ARHGEF4 Antikörper

ARHGEF4 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7118493
  • Target Alle ARHGEF4 Antikörper anzeigen
    ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))
    Reaktivität
    • 31
    • 11
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 25
    • 5
    • 1
    Kaninchen
    Klonalität
    • 27
    • 4
    Polyklonal
    Konjugat
    • 11
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARHGEF4 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    Rho guanine nucleotide exchange factor(GEF) 4
    Isotyp
    IgG
    Top Product
    Discover our top product ARHGEF4 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))
    Andere Bezeichnung
    ARHGEF4 (ARHGEF4 Produkte)
    Synonyme
    ARHGEF4 antikoerper, ASEF antikoerper, ASEF1 antikoerper, GEF4 antikoerper, STM6 antikoerper, 9330140K16Rik antikoerper, Asef antikoerper, ENSMUSG00000070955 antikoerper, Rho guanine nucleotide exchange factor 4 antikoerper, uncharacterized LOC100470646 antikoerper, rho guanine nucleotide exchange factor 4 antikoerper, Rho guanine nucleotide exchange factor (GEF) 4 antikoerper, ARHGEF4 antikoerper, arhg4 antikoerper, LOC100470646 antikoerper, LOC100544917 antikoerper, Arhgef4 antikoerper
    Hintergrund
    Synonyms:KIAA1112 Background:Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
    Molekulargewicht
    72 kDa
    Gen-ID
    50649
    UniProt
    Q9NR80
    Pathways
    Neurotrophin Signalübertragung
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