CKBBP1 antikoerper, ROC2 antikoerper, SAG antikoerper, Rbx2 antikoerper, ring finger protein 7 antikoerper, RNF7 antikoerper, Rnf7 antikoerper
Hintergrund
Synonyms:RBX2, ROC2, SAG Background:Probable component of the SCF(SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.