RBM14 Antikörper

Produktnummer ABIN7118671

Produktdetails anti-RBM14 Antikörper

Target: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: RNA binding motif protein 14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu RBM14

Target: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Andere Bezeichnung: RBM14 (RBM14 Produkte)

Hintergrund: Synonyms:SIP Background:Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1(PubMed:11443112). Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex(which can induce the formation of aberrant centriolar protein complexes) by interfering with the interaction of STIL with CENPJ(PubMed:25385835).

Molekulargewicht: 70-75 kDa

Gen-ID: 10432

UniProt: Q96PK6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway