zgc:55840 antikoerper, SPF45 antikoerper, 2700027J02Rik antikoerper, RNA binding motif protein 17 antikoerper, RNA binding motif protein 17 L homeolog antikoerper, Rbm17 antikoerper, rbm17 antikoerper, RBM17 antikoerper, rbm17.L antikoerper
Hintergrund
Synonyms:SPF45 Background:Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia.