RBM25 Antikörper
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- Target Alle RBM25 Antikörper anzeigen
- RBM25 (RNA Binding Motif Protein 25 (RBM25))
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Reaktivität
- Maus, Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RBM25 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- RNA binding motif protein 25
- Isotyp
- IgG
- Top Product
- Discover our top product RBM25 Primärantikörper
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anti-RNA Binding Motif Protein 25 (RBM25) (AA 614-843) antibody
RBM25 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-RNA Binding Motif Protein 25 (RBM25) antibodyRBM25 Reaktivität: Maus, Human IF Wirt: Kaninchen Polyclonal unconjugated
anti-RNA Binding Motif Protein 25 (RBM25) (AA 285-334) antibodyRBM25 Reaktivität: Maus, Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Huhn, Affe, Schwein, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- RBM25 (RNA Binding Motif Protein 25 (RBM25))
- Andere Bezeichnung
- RBM25 (RBM25 Produkte)
- Hintergrund
- Synonyms:fSAP94, NET52, Protein S164, RBM25, RED120, RNA binding motif protein 25, RNA binding protein 25, RNPC7, S164 Background:RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site(5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.
- Molekulargewicht
- 110-120 kDa
- Gen-ID
- 58517
- UniProt
- P49756
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