SH3PXD2A Antikörper

Produktnummer ABIN7119018

Produktdetails anti-SH3PXD2A Antikörper

Target: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH3PXD2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: SH3 and PX domains 2A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu SH3PXD2A

Target: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Andere Bezeichnung: SH3PXD2A (SH3PXD2A Produkte)

Hintergrund: Synonyms:FISH, KIAA0418, SH3MD1, TKS5 Background:Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases(ADAMs), NADPH oxidases(NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1-or NOX3-dependent reactive oxygen species(ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.

Molekulargewicht: 140 kDa

Gen-ID: 9644

UniProt: Q5TCZ1