SMC6 Antikörper

Produktnummer ABIN7119188

Produktdetails anti-SMC6 Antikörper

Target: SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: structural maintenance of chromosomes 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu SMC6

Target: SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))

Andere Bezeichnung: SMC6 (SMC6 Produkte)

Synonyme: SMC6L1 antikoerper, SMC-6 antikoerper, hSMC6 antikoerper, 2810489L22Rik antikoerper, 3830418C19Rik antikoerper, AA990493 antikoerper, AU018782 antikoerper, AW742439 antikoerper, Smc6l1 antikoerper, mKIAA4103 antikoerper, structural maintenance of chromosomes 6 antikoerper, SMC6 antikoerper, smc6 antikoerper, Smc6 antikoerper

Hintergrund: Synonyms:SMC6L1 Background:Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT(alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex(telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies(APBs). Required for recruitment of telomeres to PML nuclear bodies. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome(PubMed:26983541).

Molekulargewicht: 130 kDa

Gen-ID: 79677

UniProt: Q96SB8