SNX27 Antikörper

Produktnummer ABIN7119360

Produktdetails anti-SNX27 Antikörper

Target: SNX27 (Sorting Nexin 27 (SNX27))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX27 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: sorting nexin family member 27

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu SNX27

Target: SNX27 (Sorting Nexin 27 (SNX27))

Andere Bezeichnung: SNX27 (SNX27 Produkte)

Synonyme: MRT1 antikoerper, MY014 antikoerper, 5730552M22Rik antikoerper, ESTM45 antikoerper, ESTM47 antikoerper, R75405 antikoerper, mKIAA0488 antikoerper, Mrt1 antikoerper, sorting nexin family member 27 antikoerper, SNX27 antikoerper, Snx27 antikoerper

Hintergrund: Synonyms:KIAA0488 Background:Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate(PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.

Molekulargewicht: 52-60 kDa

Gen-ID: 81609

UniProt: Q96L92