SART3 Antikörper
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- Target Alle SART3 Antikörper anzeigen
- SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SART3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- squamous cell carcinoma antigen recognized by T cells 3
- Isotyp
- IgG
- Top Product
- Discover our top product SART3 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))
- Andere Bezeichnung
- SART3 (SART3 Produkte)
- Synonyme
- SART3 antikoerper, DKFZp469J2418 antikoerper, si:ch211-191d15.4 antikoerper, wu:fc51h03 antikoerper, DSAP1 antikoerper, P100 antikoerper, RP11-13G14 antikoerper, TIP110 antikoerper, p110 antikoerper, p110(nrb) antikoerper, AU045857 antikoerper, mKIAA0156 antikoerper, squamous cell carcinoma antigen recognized by T-cells 3 antikoerper, squamous cell carcinoma antigen recognized by T-cells 3 L homeolog antikoerper, squamous cell carcinoma antigen recognized by T cells 3 antikoerper, SART3 antikoerper, sart3 antikoerper, sart3.L antikoerper, Sart3 antikoerper
- Hintergrund
- Synonyms:DSAP1, hSART 3, KIAA0156, P100, p110, p110(nrb), RP11 13G14, SART 3, SART3, TIP110, Background:U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation(PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites(PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly(PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair(PubMed:24526689). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC(By similarity).
- Molekulargewicht
- 110 kDa
- Gen-ID
- 9733
- UniProt
- Q15020
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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