TAF1C antikoerper, Tafi95 antikoerper, mTAFI95 antikoerper, MGC:39976 antikoerper, SL1 antikoerper, TAFI110 antikoerper, TAFI95 antikoerper, TATA-box binding protein associated factor, RNA polymerase I subunit C antikoerper, TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa antikoerper, TATA-box binding protein associated factor, RNA polymerase I, C antikoerper, TATA-box binding protein associated factor, RNA polymerase 1 subunit C antikoerper, TAF1C antikoerper, Taf1c antikoerper
Hintergrund
Synonyms: Background:Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.