TBC1D17 Antikörper
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- Target Alle TBC1D17 Antikörper anzeigen
- TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TBC1D17 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- TBC1 domain family, member 17
- Isotyp
- IgG
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- Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))
- Andere Bezeichnung
- TBC1D17 (TBC1D17 Produkte)
- Synonyme
- BC017607 antikoerper, TBC1 domain family member 17 antikoerper, TBC1 domain family, member 17 antikoerper, TBC1D17 antikoerper, Tbc1d17 antikoerper
- Hintergrund
- Synonyms: Background:Probable GTPase-activating protein for Rab8, its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor(TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment(ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50, the function requires its catalytic activity, however, the involved Rab is not known.
- Molekulargewicht
- 73 kDa
- Gen-ID
- 79735
- UniProt
- Q9HA65
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