TEX14 Antikörper

Produktnummer ABIN7119846

Produktdetails anti-TEX14 Antikörper

Target: TEX14 (Testis Expressed 14 (TEX14))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TEX14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: testis expressed 14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu TEX14

Target: TEX14 (Testis Expressed 14 (TEX14))

Andere Bezeichnung: TEX14 (TEX14 Produkte)

Synonyme: CT113 antikoerper, C85585 antikoerper, testis expressed 14, intercellular bridge forming factor antikoerper, testis expressed gene 14 antikoerper, inactive serine/threonine-protein kinase TEX14 antikoerper, TEX14 antikoerper, Tex14 antikoerper, tex14 antikoerper, LOC100389169 antikoerper

Hintergrund: Synonyms:SGK307 Background:Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro(By similarity).

Molekulargewicht: 180-200 kDa, 106 kDa

Gen-ID: 56155

UniProt: Q8IWB6

Pathways: Maintenance of Protein Location