TSPAN12 Antikörper
-
- Target Alle TSPAN12 Antikörper anzeigen
- TSPAN12 (Tetraspanin 12 (TSPAN12))
-
Reaktivität
- Human, Ratte, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser TSPAN12 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- tetraspanin 12
- Isotyp
- IgG
- Top Product
- Discover our top product TSPAN12 Primärantikörper
-
anti-Tetraspanin 12 (TSPAN12) (AA 111-224) antibody
TSPAN12 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) antibodyTSPAN12 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 232-259), (C-Term) antibodyTSPAN12 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB22652 unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 111-224) antibodyTSPAN12 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 185-234) antibodyTSPAN12 Reaktivität: Human, Ratte, Maus, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Fledermaus, Affe, Schwein WB, IHC (p), IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) antibodyTSPAN12 Reaktivität: Human WB, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 1-100) antibodyTSPAN12 Reaktivität: Human, Ratte ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (AA 179-228) antibodyTSPAN12 Reaktivität: Human, Ratte, Maus, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Fledermaus, Affe, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
anti-Tetraspanin 12 (TSPAN12) (Middle Region) antibodyTSPAN12 Reaktivität: Human, Ratte, Maus, Hund WB Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- WB: 1:200-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
-
- Target
- TSPAN12 (Tetraspanin 12 (TSPAN12))
- Andere Bezeichnung
- TSPAN12 (TSPAN12 Produkte)
- Synonyme
- tm4sf12 antikoerper, zgc:63880 antikoerper, EVR5 antikoerper, NET-2 antikoerper, NET2 antikoerper, TM4SF12 antikoerper, 9030619E17 antikoerper, AI426782 antikoerper, AI663988 antikoerper, AW111457 antikoerper, Tm4sf12 antikoerper, tetraspanin-7 antikoerper, tetraspanin 12 antikoerper, LOC412465 antikoerper, TSPAN12 antikoerper, tspan12 antikoerper, Tspan12 antikoerper
- Hintergrund
- Synonyms:NET 2, NET2, Tetraspan NET 2, tetraspanin 12, TM4SF12, Tspan 12, TSPAN12 Background:Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin(NDP) signal transduction. Acts in concert with norrin(NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin(CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin(NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin(CTNNB1)(By similarity). Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. Activates ADAM10-dependent cleavage activity of amyloid precursor protein(APP). Activates MMP14/MT1-MMP-dependent cleavage activity.
- Molekulargewicht
- 28 kDa
- Gen-ID
- 23554
- UniProt
- O95859
-
