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Tubulin Antikörper (acLys40)

TUB Reaktivität: Human, Maus, Ratte, Hund WB, ELISA, IHC, IF Wirt: Maus Monoclonal 6A10 unconjugated
Produktnummer ABIN7120355
  • Target Alle Tubulin (TUB) Antikörper anzeigen
    Tubulin (TUB)
    Bindungsspezifität
    • 2
    • 1
    • 1
    acLys40
    Reaktivität
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund
    Wirt
    • 7
    • 3
    • 1
    Maus
    Klonalität
    • 7
    • 4
    Monoklonal
    Konjugat
    • 11
    Dieser Tubulin Antikörper ist unkonjugiert
    Applikation
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Protein A+G purification
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    tubulin, alpha 1a
    Klon
    6A10
    Isotyp
    IgG1
    Top Product
    Discover our top product TUB Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:5000, IF: 1:20-1:200, IHC: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    Tubulin (TUB)
    Andere Bezeichnung
    tubulin (TUB Produkte)
    Synonyme
    4t antikoerper, B4t antikoerper, BETA 98B antikoerper, CG4869 antikoerper, DTB1 antikoerper, Dmbeta4 antikoerper, Dmel\\CG4869 antikoerper, T antikoerper, Tub antikoerper, beta-Tub antikoerper, beta-Tub97EF antikoerper, beta-tub antikoerper, beta4 antikoerper, beta4t antikoerper, beta97F antikoerper, betaTub4 antikoerper, betaTub98BC antikoerper, betaTub98C antikoerper, beta-Tubulin at 97EF antikoerper, betaTub97EF antikoerper
    Hintergrund
    Synonyms:Acetylated alpha tubulin, Acetylated tubulin, acetylated-a-tubulin, acetyl-a-tubulin, alpha tubulin, Alpha tubulin 3, tubulin,TUBA1A Background:Tubulin, composed of heterodimers of alpha and beta tubulin, is the mainly component of microtubules which play important roles in cell motility, mitosis, and intracellular vesicle transport. Both alpha and beta tubulin undergo several posttranslational modifications such as polyglutamylation and acetylation/deacetylation. Tubulin acetylation occurs on lysine-40 at the N-terminal of alpha tubulin and is conserved across species. The histone deacetylase HDAC6 and SIRT2 has been identified as tubulin deacetylases. Reversible acetylation of alpha tubulin may be implicated in regulating microtubule stability, cell motility, and axon regeneration. The level of acetylated tubulin has been linked to epithelial malignancies and sensitivity to chemotherapy. In addition, acetylated tubulin has been widely used as a marker for primary cilia. This antibody is specific to the acetylated tubulin, it does not recognize non-acetylated tubulin.
    Molekulargewicht
    52 kDa
    Gen-ID
    7846
    UniProt
    Q71U36
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