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USP11 Antikörper

USP11 Reaktivität: Human WB, ELISA, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7120493
  • Target Alle USP11 Antikörper anzeigen
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    Reaktivität
    • 49
    • 13
    • 12
    • 1
    • 1
    Human
    Wirt
    • 42
    • 7
    • 1
    Kaninchen
    Klonalität
    • 35
    • 15
    Polyklonal
    Konjugat
    • 26
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser USP11 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 20
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    ubiquitin specific peptidase 11
    Isotyp
    IgG
    Top Product
    Discover our top product USP11 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:1000-1:10000, IF: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    Andere Bezeichnung
    USP11 (USP11 Produkte)
    Hintergrund
    Synonyms:Deubiquitinating enzyme 11, Ubiquitin thiolesterase 11, UHX1, USP11 Background:Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains(PubMed:12084015, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:20233726, PubMed:24724799). Inhibits the degradation of target proteins by the proteasome(PubMed:12084015). Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains(in vitro)(PubMed:24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation(PubMed:17897950, PubMed:19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks(PubMed:15314155, PubMed:20233726).
    Molekulargewicht
    110 kDa
    Gen-ID
    8237
    UniProt
    P51784
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