USP20 Antikörper
-
- Target Alle USP20 Antikörper anzeigen
- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser USP20 Antikörper ist unkonjugiert
-
Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- ubiquitin specific peptidase 20
- Isotyp
- IgG
- Top Product
- Discover our top product USP20 Primärantikörper
-
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 814-844), (C-Term) antibody
USP20 Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB4351 unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibodyUSP20 Reaktivität: Human, Affe IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibodyUSP20 Reaktivität: Human, Hund, Kaninchen, Pferd, Huhn, Schwein, Affe, Rind (Kuh), Fledermaus IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibodyUSP20 Reaktivität: Human, Hund, Kaninchen, Pferd, Hamster IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 252-349) antibodyUSP20 Reaktivität: Human ELISA, WB Wirt: Maus Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 1-913) antibodyUSP20 Reaktivität: Human IP Wirt: Kaninchen Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 252-349) antibodyUSP20 Reaktivität: Human ELISA, WB Wirt: Maus Monoclonal 1A6 unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 1-913) antibodyUSP20 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (C-Term) antibodyVerified USP20 Reaktivität: Human ELISA, WB, IHC Wirt: Ziege Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 361-410) antibodyUSP20 Reaktivität: Human, Kaninchen, Ratte, Huhn, Affe, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- WB: 1:200-1:2000, IHC: 1:20-1:200,IP: 1:200-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
-
- Target
- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
- Andere Bezeichnung
- USP20 (USP20 Produkte)
- Hintergrund
- Synonyms:Deubiquitinating enzyme 20, hVDU2, KIAA1003, LSFR3A, Ubiquitin thiolesterase 20, USP20, VDU2 Background:Deubiquitinating enzyme involved in beta-2 adrenergic receptor(ADRB2) recycling. Acts as a regulator of G-protein coupled receptor(GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor(ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'-and 'Lys-63'-linked polyubiquitin chains.
- Molekulargewicht
- 110 kDa
- Gen-ID
- 10868
- UniProt
- Q9Y2K6
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
-
