WDR24 Antikörper

Produktnummer ABIN7120816

Produktdetails anti-WDR24 Antikörper

Target: WDR24 (WD Repeat Domain 24 (WDR24))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WDR24 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: WD repeat domain 24

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000, IP: 1:200-1:2000, IF: 1:10-1:100, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu WDR24

Target: WDR24 (WD Repeat Domain 24 (WDR24))

Andere Bezeichnung: WDR24 (WDR24 Produkte)

Synonyme: C16orf21 antikoerper, JFP7 antikoerper, BC037651 antikoerper, wu:fd05f12 antikoerper, zgc:55946 antikoerper, WD repeat domain 24 antikoerper, WD repeat domain 24 L homeolog antikoerper, WDR24 antikoerper, Wdr24 antikoerper, wdr24 antikoerper, wdr24.L antikoerper

Hintergrund: Synonyms:C16orf21, DKFZp434F054, JFP7, WD repeat domain 24, WDR24 Background:As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2(PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux(PubMed:27166823).

Molekulargewicht: 102 kDa

Gen-ID: 84219

UniProt: Q96S15