GPR177/WLS Antikörper
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- Target Alle GPR177/WLS (WLS) Antikörper anzeigen
- GPR177/WLS (WLS) (Wntless Homolog (WLS))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GPR177/WLS Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- G protein-coupled receptor 177
- Isotyp
- IgG
- Top Product
- Discover our top product WLS Primärantikörper
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anti-Wntless Homolog (WLS) (AA 123-232) antibody
WLS Reaktivität: Human ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Wntless Homolog (WLS) (N-Term) antibodyWLS Reaktivität: Human, Maus, Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Wntless Homolog (WLS) (N-Term) antibodyWLS Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Wntless Homolog (WLS) (AA 53-102) antibodyWLS Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Schwein, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Wntless Homolog (WLS) antibodyWLS Reaktivität: Human, Maus, Ratte ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Wntless Homolog (WLS) (Middle Region) antibodyWLS Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- GPR177/WLS (WLS) (Wntless Homolog (WLS))
- Andere Bezeichnung
- GPR177 (WLS Produkte)
- Hintergrund
- Synonyms:C1orf139, EVI, G protein coupled receptor 177, GPR177, Protein wntless homolog, Sprinter, WLS, Wntless Background:GPR177, also known as Wntless (WLS) or Evi, is an evolutionarily conserved transmembrane protein necessary for Wnt protein secretion. GPR177 localizes to compartments of the secretory pathway, including the ER, Golgi apparatus, endosomes, and plasma membrane. GPR177 is overexpressed in several cancer types including glioma and gastric cancer. Several isoforms of GPR177 exist due to the alternative splicing, with predicted MW around 62 and 51 kDa, respectively. The sequence can be processed by removing the signal peptide, which generates a mature form of 45-46 kDa. In addition, slow migragrating band above 62 kDa can also be detected because GPR177 is modified by N-linked glycosylation (PMID: 20549736).
- Molekulargewicht
- 46-62 kDa
- Gen-ID
- 79971
- UniProt
- Q5T9L3
- Pathways
- WNT Signalweg
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