YTHDC2 Antikörper

Produktnummer ABIN7120902

Produktdetails anti-YTHDC2 Antikörper

Target: YTHDC2 (YTH Domain Containing 2 (YTHDC2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YTHDC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: 3'-5' RNA helicase YTHDC2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IF: 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu YTHDC2

Target: YTHDC2 (YTH Domain Containing 2 (YTHDC2))

Andere Bezeichnung: YTHDC2 (YTHDC2 Produkte)

Synonyme: 3010002F02Rik antikoerper, BC037178 antikoerper, CAHL antikoerper, YTH domain containing 2 antikoerper, Ythdc2 antikoerper, YTHDC2 antikoerper

Hintergrund: Synonyms:YTHDC2, CAHL Background:This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.

Molekulargewicht: 160 kDa

UniProt: Q9H6S0