TOM1L1 Antikörper

Produktnummer ABIN7504136

Produktdetails anti-TOM1L1 Antikörper

Target: TOM1L1 (Target of Myb1 (Chicken)-Like 1 (TOM1L1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TOM1L1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität: Tom1 (target of Myb 1) is a 492 amino acid cytoplasmic protein that belongs to the Tom1 family. Widely expressed with highest expression in heart, liver, placenta and skeletal muscle, Tom1 is thought to be involved in intracellular trafficking and may be associated with the translocation of ubiquitinated proteins to early endosomes for degradation. Tom1 contains one GAT domain and one VHS domain through which it interacts and complexes with proteins such as Tollip and endofin (also known as SARA). These interactions recruit Tom1 to the endosome, allowing it to participate in the endosomal trafficking of ubiquitin-tagged proteins.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human TOM1L1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Positive Control: Human kidney.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Haltbarkeit: 24 months

Details zu TOM1L1

Target: TOM1L1 (Target of Myb1 (Chicken)-Like 1 (TOM1L1))

Andere Bezeichnung: TOM1L1 (TOM1L1 Produkte)

Synonyme: MGC52738 antikoerper, srcasm antikoerper, TOM1L1 antikoerper, OK/KNS-CL.3 antikoerper, SRCASM antikoerper, RGD1562626 antikoerper, Srcasm antikoerper, 2310045L10Rik antikoerper, C80573 antikoerper, target of myb1 like 1 membrane trafficking protein L homeolog antikoerper, target of myb1 like 1 membrane trafficking protein antikoerper, target of myb1-like 1 (chicken) antikoerper, tom1l1.L antikoerper, TOM1L1 antikoerper, tom1l1 antikoerper, Tom1l1 antikoerper

Hintergrund: 2310045L10Rik, C80573, OK/KNS CL.3, Src activating and signaling molecule, SRCASM, Target of Myb like protein 1, Target of myb1 (chicken) homolog like 1, Target of myb1 (chicken) like 1, TOM1 like protein 1, TOM1L1 protein,TOM1L1 (Target of Myb1 Like 1 Membrane Trafficking Protein)
Cellular localisation: Golgi apparatus > Golgi stack. Endosome membrane.

Molekulargewicht: 53kDa.

Gen-ID: 10040, 153504

UniProt: O75674