JAZF1 Antikörper (AA 1-130)
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- Target Alle JAZF1 Antikörper anzeigen
- JAZF1 (JAZF Zinc Finger 1 (JAZF1))
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Bindungsspezifität
- AA 1-130
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser JAZF1 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP)
- Spezifität
- JAZF1 (juxtaposed with another zinc finger protein 1), also known as TIP27 (TAK1-interacting protein 27) or ZNF802 (zinc finger protein 802), is a 243 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Existing as multiple alternatively spliced isoforms, JAZF1 interacts with the nuclear orphan receptor TR4 and is thought to function as a transcriptional repressor, effectively down-regulation the expression of TR4. Chromosomal aberrations in the gene encoding JAZF1 are associated with the pathogenesis of endometrial stromal tumors, suggesting a role for JAZF1 in carcinogenesis.
- Kreuzreaktivität (Details)
- Human. Predicted to react in Mouse.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment (around aa1-130) of human JAZF1 protein (exact sequence is proprietary)
- Isotyp
- IgG2a
- Top Product
- Discover our top product JAZF1 Primärantikörper
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- Applikationshinweise
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Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or U87 cells. Ubiquitous tissue expression.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- JAZF1 (JAZF Zinc Finger 1 (JAZF1))
- Andere Bezeichnung
- JAZF1 (JAZF1 Produkte)
- Synonyme
- TIP27 antikoerper, ZNF802 antikoerper, JAZF1 antikoerper, AI591476 antikoerper, C820002C15 antikoerper, Jaz1 antikoerper, Tip27 antikoerper, zgc:103778 antikoerper, JAZF zinc finger 1 antikoerper, JAZF zinc finger 1b antikoerper, JAZF1 antikoerper, Jazf1 antikoerper, jazf1b antikoerper
- Hintergrund
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DKFZp761K2222, TIP27, ZNF802,JAZF1 (Transcription Corepressor)
Cellular localisation: Nucleus. - Molekulargewicht
- 27.08kDa
- Gen-ID
- 221895, 368944
- UniProt
- Q86VZ6
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