CNOT10 Antikörper

Produktnummer ABIN7126458

Produktdetails anti-CNOT10 Antikörper

Target: CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CNOT10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Coating (Coat), Flow Cytometry (FACS)

Spezifität: CNOT10 is a subunit of the CCR4-NOT complex which consists of at least five other CNOT subunit proteins and TAB182. The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription, as well as in mRNA degradation. Various subunits (e.g. CNOT1, CNOT3) are uniquely involved in influencing nuclear hormone receptor activities. In effect, this complex has an important role as a transcription regulator and repressor of nuclear receptor signaling that is relevant to the molecular pathways involved in cancer. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human CNOT10 protein

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu CNOT10

Target: CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))

Andere Bezeichnung: CNOT10 (CNOT10 Produkte)

Synonyme: 2600001P13Rik antikoerper, cnot10 antikoerper, im:7139356 antikoerper, zgc:152939 antikoerper, cnot10-a antikoerper, cnot10-b antikoerper, CCR4-NOT transcription complex subunit 10 antikoerper, CCR4-NOT transcription complex, subunit 10 antikoerper, CCR4-NOT transcription complex subunit 10 S homeolog antikoerper, CCR4-NOT transcription complex subunit 10 L homeolog antikoerper, CNOT10 antikoerper, Cnot10 antikoerper, cnot10.S antikoerper, cnot10 antikoerper, cnot10.L antikoerper

Hintergrund: FLJ12890, FLJ13165,CCR4-NOT transcription complex, subunit 10 (CNOT10)
Cellular localisation: Cytoplasm. Mitochondrion and Nucleus, PML body.

Molekulargewicht: 82.31kDa

Gen-ID: 25904, 444851

UniProt: Q9H9A5