Rekombinanter RPSA/Laminin Receptor Antikörper

Produktnummer ABIN7126636

Produktdetails anti-RPSA/Laminin Receptor Antikörper

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RPSA/Laminin Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität: Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human RPSA protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: MCF-7, MDA-MB-453or HEK293 cells.Human breast, colon or ovarian carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu RPSA/Laminin Receptor

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Andere Bezeichnung: RPSA (RPSA Produkte)

Synonyme: 37LRP antikoerper, 67LR antikoerper, LBP/p40 antikoerper, LRP/LR antikoerper, LamR antikoerper, rpsa antikoerper, LamR1 antikoerper, RPSA antikoerper, LAMBR antikoerper, LAMR1 antikoerper, LBP antikoerper, LRP antikoerper, NEM/1CHD4 antikoerper, SA antikoerper, lamR antikoerper, p40 antikoerper, 67kDa antikoerper, 67lr antikoerper, AL022858 antikoerper, Lamr antikoerper, Lamr1 antikoerper, Lamrl1 antikoerper, MLR antikoerper, P40 antikoerper, P40-3 antikoerper, P40-8 antikoerper, lamr1 antikoerper, zgc:55831 antikoerper, zgc:77824 antikoerper, DMRT1 antikoerper, 40S ribosomal protein SA antikoerper, 67kD laminin receptor antikoerper, ribosomal protein SA antikoerper, rssa antikoerper, rpsa antikoerper, RPSA antikoerper, Rpsa antikoerper, LOC100144340 antikoerper

Hintergrund: 34/67 kDa Laminin Receptor, 37 kDa Laminin Receptor precursor, 37/67 kDa Laminin Receptor, 37LRP, 40S Ribosomal Protein SA, 67 kDa Laminin Receptor, 67LR, Colon Carcinoma Laminin-binding Protein, LAMBR, Laminin receptor 1, Laminin-binding Protein precursor p40, LAMR1, LBP/p40, LRP/LR, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, Ribosomal Protein SA (RPSA),Laminin Receptor/ RPSA (Marker of Metastatic Potential)
Cellular localisation: Cell Surface,Cytoplasmic and Nuclear

Molekulargewicht: 37-67kDa

Gen-ID: 3921, 449909

UniProt: P08865

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly