SMAD9 Antikörper
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- Target Alle SMAD9 Antikörper anzeigen
- SMAD9 (SMAD Family Member 9 (SMAD9))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SMAD9 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS)
- Spezifität
- Smad proteins, the mammalian homologs of the Drosophila mothers against dpp (Mad) have been implicated as downstream effectors of TGFi²/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFi² and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFi² signaling by interfering with TGFi²-mediated phosphorylation of other Smad family members.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human SMAD9 protein
- Isotyp
- IgG1
- Top Product
- Discover our top product SMAD9 Primärantikörper
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- Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, U87 or Ramos cells.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- SMAD9 (SMAD Family Member 9 (SMAD9))
- Andere Bezeichnung
- SMAD9 (SMAD9 Produkte)
- Synonyme
- SMAD8 antikoerper, MADH6 antikoerper, MADH9 antikoerper, PPH2 antikoerper, SMAD8A antikoerper, SMAD8B antikoerper, Madh8 antikoerper, Madh9 antikoerper, Smad8 antikoerper, SMAD family member 9 antikoerper, SMAD9 antikoerper, smad9 antikoerper, Smad9 antikoerper
- Hintergrund
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MAD homolog 9, Madh6, Mothers against decapentaplegic homolog 9, Mothers against DPP homolog 9, SMAD family member 9, SMAD, mothers against DPP homolog 9 (Drosophila), SMAD8A, SMAD8B, Smad9,SMAD9
Cellular localisation: Cytoplasm. Nucleus. In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4. - Molekulargewicht
- 52.4kDa
- Gen-ID
- 4093, 123119
- UniProt
- O15198
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