ZBTB7B Antikörper

Produktnummer ABIN7126763

Produktdetails anti-ZBTB7B Antikörper

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ZBTB7B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Spezifität: TH-POK (T-helper-inducing POZ/Kr ppel-like factor), also known as zinc finger protein 67 (ZFP67), zinc finger and BTB domain-containing protein 7B or Kr ppel-related zinc finger protein cKrox, is a 539 amino acid protein that contains one BTB (POZ) domain and four C2H2-type zinc fingers. Localized to the nucleus, TH-POK functions primarily as a key regulator of lineage commitment of immature T-cell precursors. Specifically, the presence of TH-POK directs positively selected thymocytes to the CD4 lineage, whereas its absence causes default development to the CD8 lineage. TH-POK also functions as a transcriptional repressor of various other genes, such as COL1A1, COL1A2 and Fibronectin.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human ZBTB7B protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu ZBTB7B

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Andere Bezeichnung: ZBTB7B (ZBTB7B Produkte)

Synonyme: THPOK antikoerper, ZBTB15 antikoerper, ZFP-67 antikoerper, ZFP67 antikoerper, ZNF857B antikoerper, c-KROX antikoerper, hcKROX antikoerper, Thpok antikoerper, Zfp67 antikoerper, c-Krox antikoerper, ZBTB7B antikoerper, zbtb7b antikoerper, MGC130914 antikoerper, zinc finger and BTB domain containing 7B antikoerper, kruppel-related zinc finger protein hcKrox antikoerper, ZBTB7B antikoerper, Zbtb7b antikoerper, zbtb7b antikoerper

Hintergrund: CKrox, hcKrox, T helper inducing POZ/Kruppel like factor, Th-POK, ThPOK, ZBTB15, ZBTB7B, ZFP67, Zinc finger and BTB domain containing 15, Zinc finger and BTB domain containing 7B, Zinc finger protein 67 homolog, Zinc finger protein 857B, Zinc finger protein ThPOK, ZNF857B,Th-Pok / ZBTB7B
Cellular localisation: Nucleus.

Molekulargewicht: 58/80kDa

Gen-ID: 51043, 729279

UniProt: O15156