Rekombinanter Phosphoglucomutase 5 Antikörper

Produktnummer ABIN7126786

Produktdetails anti-Phosphoglucomutase 5 Antikörper

Target: Phosphoglucomutase 5 (PGM5)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Phosphoglucomutase 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Coating (Coat), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität: Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4 % of the human genome.

Kreuzreaktivität (Details): Human, Cow, Mouse, Rat and Rabbit. Predicted to react with Porcine, Avian, and Frog.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Cytoskeletal fraction of the human myometrium tissue extract

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order antibody without BSA),Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human heart muscle or smooth muscle (IHC).Mouse heart tissue lysate (WB).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu Phosphoglucomutase 5

Target: Phosphoglucomutase 5 (PGM5)

Andere Bezeichnung: PGM5 (PGM5 Produkte)

Synonyme: PGM5 antikoerper, si:dkey-91m11.4 antikoerper, PGMRP antikoerper, 4833423B07 antikoerper, 9530034F03Rik antikoerper, D830025G17 antikoerper, aciculin antikoerper, phosphoglucomutase 5 antikoerper, PGM5 antikoerper, pgm5 antikoerper, Pgm5 antikoerper

Hintergrund: Aciculin, PGM-RP, PGM5, PGMRP, phosphoglucomutase 5, Phosphoglucomutase-like protein 5, Phosphoglucomutase-related protein,Aciculin / Phosphoglucomutase 5 (PGM5)
Cellular localisation: Cytoplasm

Molekulargewicht: 56kDa

Gen-ID: 5239, 307835

UniProt: Q15124

Pathways: Cellular Glucan Metabolic Process