Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

POLE3 Antikörper

POLE3 Reaktivität: Human IF, ELISA, IP, FACS, Coat Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN7126802
  • Target Alle POLE3 Antikörper anzeigen
    POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
    Reaktivität
    • 39
    • 20
    • 16
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 34
    • 5
    Maus
    Klonalität
    • 37
    • 2
    Monoklonal
    Konjugat
    • 25
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser POLE3 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 9
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS), Coating (Coat)
    Spezifität
    DNA replication is initiated by the binding of initiation factors to the origin of replication. Nucleosomes inhibit access to the replication machinery at these origin sequences. Nucleosome remodeling factors increase the accessibility of nucleosomal DNA to transcriptional regulators. CHRAC15 and CHRAC17 are subunits of the nucleosomal remodeling factor CHRAC (chromatin accessibility complex), which increases the accessibility of nucleosomal DNA in an ATP-dependent manner. Unlike other known chromatin remodeling factors, CHRAC also functions during chromatin assembly by using ATP to convert irregular chromatin into a regular array of nucleosomes with even spacing. This conversion process occurs when CHRAC organizes randomly deposited histones into a regularly spaced array. In the presence of CHRAC, the nucleosomal ATPase ISWI catalyzes several ATP-dependent transitions of chromatin structure.
    Kreuzreaktivität (Details)
    Human. Predicted to react in Mouse, Rat and Xenopus.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length human POLE3 protein
    Isotyp
    IgG2a
    Top Product
    Discover our top product POLE3 Primärantikörper
  • Applikationshinweise

    Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells),Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or K562 cells.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))
    Andere Bezeichnung
    POLE3 (POLE3 Produkte)
    Synonyme
    NCU04548.1 antikoerper, GB14966 antikoerper, zgc:73351 antikoerper, 1810034K18Rik antikoerper, YBL1 antikoerper, CHARAC17 antikoerper, CHRAC17 antikoerper, p17 antikoerper, DNA polymerase epsilon 3, accessory subunit antikoerper, polymerase (DNA directed), epsilon 3, accessory subunit antikoerper, DNA polymerase epsilon antikoerper, DNA polymerase epsilon p17 subunit antikoerper, DNA polymerase epsilon subunit 3 antikoerper, polymerase (DNA directed), epsilon 3 (p17 subunit) antikoerper, POLE3 antikoerper, pole3 antikoerper, NCU04548 antikoerper, CpipJ_CPIJ008666 antikoerper, Bm1_04865 antikoerper, Bm1_07285 antikoerper, CTRG_00708 antikoerper, LOAG_09571 antikoerper, LOC726923 antikoerper, Pole3 antikoerper
    Hintergrund
    Arsenic transactivated protein, ASTP, CHRAC17, Chromatin accessibility complex 17 kDa protein, DNA polymerase II subunit 3, Histone fold protein CHRAC17, HuCHRAC17, Polymerase (DNA directed) epsilon 3 (POLE3), YBL1,POLE3 / CHRAC17
    Cellular localisation: Nucleus.
    Molekulargewicht
    16.86kDa
    Gen-ID
    54107, 108112
    UniProt
    Q9NRF9
    Pathways
    DNA Reparatur
Sie sind hier:
Kundenservice