HOMEZ Antikörper
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- Target Alle HOMEZ Antikörper anzeigen
- HOMEZ (Homeobox and Leucine Zipper Encoding (HOMEZ))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser HOMEZ Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- Homeodomain-containing proteins function as transcription factors that typically switch on cascades of other genes. Usually homeodomain proteins act in the promoter region of their target genes as complexes with other transcription factors, leading to much higher target specificity than a single homeodomain protein. HOMEZ (Homeobox and leucine zipper protein) is a 525 amino acid nuclear protein that contains 3 atypical homeodomains, 2 leucine zipper-like motifs, proline and serine-rich motifs and an acidic domain. Within homeodomain 2, it contains a putative nuclear localization signal. HOMEZ shares significant sequence similarity with mouse ZHX1 and sequences that are homologous to HOMEZ are restricted to vertebrates. Likely functioning as a transcription regulator, HOMEZ is ubiquitously expressed with highest levels found in in ovary, testis, kidney, fetal lung and kidney.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human HOMEZ protein
- Isotyp
- IgG2b
- Top Product
- Discover our top product HOMEZ Primärantikörper
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- Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human testis, kidney or fetal lung.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- HOMEZ (Homeobox and Leucine Zipper Encoding (HOMEZ))
- Andere Bezeichnung
- HOMEZ (HOMEZ Produkte)
- Synonyme
- KIAA1443 antikoerper, mKIAA1443 antikoerper, homeobox and leucine zipper encoding antikoerper, homeobox and leucine zipper encoding L homeolog antikoerper, homeodomain leucine zipper-encoding gene antikoerper, Homez antikoerper, homez.L antikoerper, HOMEZ antikoerper
- Hintergrund
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KIAA1443, Homeodomain leucine zipper-containing factor,Homeobox and Leucine Zipper Encoding / HOMEZ
Cellular localisation: Nucleus. - Molekulargewicht
- 61.24kDa
- Gen-ID
- 57594, 632332
- UniProt
- Q8IX15
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