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Rekombinanter S100P Antikörper (C-Term)

S100P Reaktivität: Human IHC (f) Wirt: Kaninchen Monoclonal unconjugated Recombinant Antibody
Produktnummer ABIN7126919
  • Target Alle S100P Antikörper anzeigen
    S100P (S100 Calcium Binding Protein P (S100P))
    Antikörpertyp
    Recombinant Antibody
    Bindungsspezifität
    • 9
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 44
    • 1
    • 1
    Human
    Wirt
    • 36
    • 8
    Kaninchen
    Klonalität
    • 27
    • 17
    Monoklonal
    Konjugat
    • 22
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser S100P Antikörper ist unkonjugiert
    Applikation
    • 23
    • 17
    • 11
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.
    Kreuzreaktivität (Details)
    Human.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant fragment corresponding to C-terminal of human S100P protein
    Isotyp
    IgG
    Top Product
    Discover our top product S100P Primärantikörper
  • Applikationshinweise

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human pancreatic adenocarcinoma, placenta or spleen tissue.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    S100P (S100 Calcium Binding Protein P (S100P))
    Andere Bezeichnung
    S100P (S100P Produkte)
    Synonyme
    MIG9 antikoerper, S100P antikoerper, S100p antikoerper, S100 calcium binding protein P antikoerper, S100 calcium binding protein B antikoerper, S100 calcium binding protein P pseudogene antikoerper, S100P antikoerper, s100p antikoerper, S100b antikoerper, S100p antikoerper, Gm40318 antikoerper
    Hintergrund
    Migration inducing gene 9 (MIG9), S100E, S100 calcium binding protein P,S100P
    Cellular localisation: Nucleus. Cytoplasm. Colocalizes with S100PBP in the nucleus.
    Molekulargewicht
    10kDa
    Gen-ID
    6286, 2962
    UniProt
    P25815
    Pathways
    Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteine
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