SCXA Antikörper

Produktnummer ABIN7126933

Produktdetails anti-SCXA Antikörper

Target: SCXA (Scleraxis (SCXA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SCXA Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Spezifität: Transcription factors are proteins that bind DNA adjacent to genes and control the production of mRNA transcripts. Scleraxis (basic helix-loop-helix transcription factor scleraxis) is a 201 amino acid protein that dimerizes with another bHLH protein to initiate transcription. Scleraxis is known to play a role in formation of mesoderm and somite-derived chondrogenic lineages. Scleraxis localizes to the nucleus and contains one bHLH domain. bHLH transcription factors, in general, function in cellular differentiation, proliferation, and oncogene regulation. The gene encoding Scleraxis maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human SCXA protein

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu SCXA

Target: SCXA (Scleraxis (SCXA))

Andere Bezeichnung: SCX (SCXA Produkte)

Synonyme: BB114693 antikoerper, Bhlha41 antikoerper, Scl antikoerper, SCX antikoerper, bHLHa48 antikoerper, scleraxis antikoerper, scleraxis bHLH transcription factor antikoerper, Scx antikoerper, SCX antikoerper

Hintergrund: Basic helix loop helix transcription factor scleraxis, bHLHa41, bHLHa48, Class A basic helix-loop-helix protein 41, Class A basic helix-loop-helix protein 48, scleraxis homolog A, SCX, SCXB,SCXA
Cellular localisation: Nucleus.

Molekulargewicht: 22kDa

Gen-ID: 642658, 723088

UniProt: Q7RTU7