ZNF408 Antikörper
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- Target Alle ZNF408 Antikörper anzeigen
- ZNF408 (Zinc Finger Protein 408 (ZNF408))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ZNF408 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Spezifität
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the Kr ppel C2H2-type zinc-finger protein family, ZNF396 (zinc finger protein 396), also known as PRDM17 (PR domain zinc finger protein 17), is a 720 amino acid nuclear protein that contains ten C2H2-type zinc fingers. The gene encoding ZNF408 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human ZNF408 protein
- Isotyp
- IgG2b
- Top Product
- Discover our top product ZNF408 Primärantikörper
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- Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), ,Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or Raji cells. Ubiquitious nuclear expression.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- ZNF408 (Zinc Finger Protein 408 (ZNF408))
- Andere Bezeichnung
- ZNF408 (ZNF408 Produkte)
- Synonyme
- Gm1011 antikoerper, zinc finger protein 408 antikoerper, ZNF408 antikoerper, Zfp408 antikoerper, Znf408 antikoerper, znf408 antikoerper
- Hintergrund
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EVR6, PFM14, PR domain zinc finger protein 17 (PRDM17), RP72, Zinc finger protein 408 (ZNF408),ZNF408 / PRDM17 (Transcription Factor)
Cellular localisation: Nucleus. - Molekulargewicht
- 118kDa
- Gen-ID
- 79797, 60300
- UniProt
- Q9H9D4
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