GTF2IRD2 Antikörper

Produktnummer ABIN7127094

Produktdetails anti-GTF2IRD2 Antikörper

Target: GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GTF2IRD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Spezifität: The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (GTF2I repeat domain containing 2) and GTF2IRD2B (general transcription factor II-I repeat domain-containing protein 2B). Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits including facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human GTF2IRD2 protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or K562 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu GTF2IRD2

Target: GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))

Andere Bezeichnung: GTF2IRD2 (GTF2IRD2 Produkte)

Synonyme: FP630 antikoerper, GTF2IRD2 alpha antikoerper, GTF2IRD2A antikoerper, 1700012P16Rik antikoerper, GTF2I repeat domain containing 2 antikoerper, GTF2IRD2 antikoerper, Gtf2ird2 antikoerper

Hintergrund: FP630, GTF2IRD2A, GTF2IRD2 alpha,GTF2IRD2
Cellular localisation: Nucleus.

Molekulargewicht: 107kDa

Gen-ID: 84163, 647039

UniProt: Q86UP8