INSM2 Antikörper (AA 432-540)

Produktnummer ABIN7127097

Produktdetails anti-INSM2 Antikörper

Target: INSM2 (Insulinoma-Associated 2 (INSM2))

Bindungsspezifität: AA 432-540

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser INSM2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität: IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription. INSM2 may function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment of human INSM2 protein (around aa 432-540) (exact sequence is proprietary)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human pancreas tissue.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu INSM2

Target: INSM2 (Insulinoma-Associated 2 (INSM2))

Andere Bezeichnung: INSM2 (INSM2 Produkte)

Synonyme: INSM2 antikoerper, IA-6 antikoerper, IA6 antikoerper, mlt1 antikoerper, Mlt1 antikoerper, INSM transcriptional repressor 2 antikoerper, insulinoma-associated 2 antikoerper, INSM2 antikoerper, Insm2 antikoerper

Hintergrund: IA1, Insulinoma associated protein 2 (IA2), Zinc finger protein IA6,Insulinoma Associated 2 / INSM2
Cellular localisation: Nuclear

Molekulargewicht: 58kDa

Gen-ID: 84684, 62813

UniProt: Q96T92