ZMYM3 Antikörper
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- Target Alle ZMYM3 Antikörper anzeigen
- ZMYM3 (Zinc Finger Protein 261 (ZMYM3))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ZMYM3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS)
- Spezifität
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZMYM3 (zinc finger MYM-type protein 3), also known as ZNF261 (zinc finger protein 261), XFIM, DXS6673E or MYM, is a 1,370 amino acid nuclear protein that contains nine MYM-type zinc fingers. Expressed in a variety of tissues, including heart, muscle and brain, ZMYM3 is thought to function as part of a histone deacetylase-containing complex that contains other proteins, such as HDAC1 and HDAC2, and may play a role in gene silencing through the modification of chromatin structure. Defects in the gene encoding ZMYM3 that lead to chromosomal translocations may be a cause of X-linked mental retardation. Two isoforms of ZMYM3 exist due to alternative splicing events.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human ZMYM3 protein
- Isotyp
- IgG2a
- Top Product
- Discover our top product ZMYM3 Primärantikörper
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- Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or Raji cells. Ubiquitious nuclear expression.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- ZMYM3 (Zinc Finger Protein 261 (ZMYM3))
- Andere Bezeichnung
- ZMYM3 (ZMYM3 Produkte)
- Synonyme
- ZNF261 antikoerper, si:ch211-173p18.2 antikoerper, DXS6673E antikoerper, MYM antikoerper, XFIM antikoerper, ZNF198L2 antikoerper, 9030216B10Rik antikoerper, AW122925 antikoerper, DXS6673El antikoerper, Zfp261 antikoerper, zinc finger MYM-type containing 3 antikoerper, si:ch211-173p18.3 antikoerper, zinc finger, MYM-type 3 antikoerper, ZMYM3 antikoerper, si:ch211-173p18.3 antikoerper, Zmym3 antikoerper
- Hintergrund
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DXS6673E, KIAA0385, MYM, XFIM, ZFP261, Zinc finger MYM type 3, Zinc finger MYM type protein 3, Zinc finger MYM-type protein 3, Zinc finger protein 261, ZNF198L2, ZNF261,ZMYM3
Cellular localisation: Nucleus. - Molekulargewicht
- 152kDa
- Gen-ID
- 9203, 522684
- UniProt
- Q14202
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