ZNF276 Antikörper
Kurzübersicht für ZNF276 Antikörper (ABIN7127159)
Target
Alle ZNF276 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers, the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene, which encodes a DNA repair protein, is situated at the same chromosomal location as the ZNF276 gene, suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia, an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.
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Kreuzreaktivität (Details)
- Human.
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Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant full-length human ZNF276 protein
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Isotyp
- IgG2b
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Applikationshinweise
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or K562 cells.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Haltbarkeit
- 24 months
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- ZNF276 (Zinc Finger Protein 276 (ZNF276))
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Andere Bezeichnung
- ZNF276
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Hintergrund
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AW048709, D8Ertd370e, D8Ertd377e, FLJ38685, FLJ77809, HGNC:23330, ZFP276, Zinc finger protein (C2H2 type) 276, Zinc finger protein 276, Zinc finger protein 276 homolog, Zinc finger protein 477, ZNF276, ZNF477,ZNF276 (Transcription Factor)
Cellular localisation: Nucleus. Nucleoplasm. -
Molekulargewicht
- 67kDa
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Gen-ID
- 92822, 290154
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UniProt
- Q8N554
Target
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