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ZNF276 Antikörper

Dieses Anti-ZNF276-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ZNF276 in ELISA, IF, Coat, FACS und IP. Geeignet für Human.
Produktnummer ABIN7127159

Kurzübersicht für ZNF276 Antikörper (ABIN7127159)

Target

Alle ZNF276 Antikörper anzeigen
ZNF276 (Zinc Finger Protein 276 (ZNF276))

Reaktivität

  • 19
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
Human

Wirt

  • 18
  • 1
Maus

Klonalität

  • 19
Monoklonal

Konjugat

  • 14
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ZNF276 Antikörper ist unkonjugiert

Applikation

ELISA, Immunofluorescence (IF), Coating (Coat), Flow Cytometry (FACS), Immunoprecipitation (IP)
  • Spezifität

    Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers, the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene, which encodes a DNA repair protein, is situated at the same chromosomal location as the ZNF276 gene, suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia, an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.

    Kreuzreaktivität (Details)

    Human.

    Aufreinigung

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Recombinant full-length human ZNF276 protein

    Isotyp

    IgG2b
  • Applikationshinweise

    Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or K562 cells.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Haltbarkeit

    24 months
  • Target

    ZNF276 (Zinc Finger Protein 276 (ZNF276))

    Andere Bezeichnung

    ZNF276

    Hintergrund

    AW048709, D8Ertd370e, D8Ertd377e, FLJ38685, FLJ77809, HGNC:23330, ZFP276, Zinc finger protein (C2H2 type) 276, Zinc finger protein 276, Zinc finger protein 276 homolog, Zinc finger protein 477, ZNF276, ZNF477,ZNF276 (Transcription Factor)
    Cellular localisation: Nucleus. Nucleoplasm.

    Molekulargewicht

    67kDa

    Gen-ID

    92822, 290154

    UniProt

    Q8N554
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