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Rekombinanter Cytokeratin 2 Antikörper (AA 300-400)

KRT76 Reaktivität: Human IHC (f) Wirt: Kaninchen Monoclonal unconjugated Recombinant Antibody
Produktnummer ABIN7127260
  • Target Alle Cytokeratin 2 (KRT76) Antikörper anzeigen
    Cytokeratin 2 (KRT76) (Cytokeratin-2P (KRT76))
    Antikörpertyp
    Recombinant Antibody
    Bindungsspezifität
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 300-400
    Reaktivität
    • 39
    • 13
    • 8
    • 1
    • 1
    Human
    Wirt
    • 27
    • 11
    • 1
    Kaninchen
    Klonalität
    • 26
    • 13
    Monoklonal
    Konjugat
    • 23
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser Cytokeratin 2 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 12
    • 11
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation. This antibody can detect high molecular weight CK1, CK2, CK3, CK4, CK5, CK6, CK7 and CK8. It is usually used in a cytokeratin cocktail with type I cytokeratins antibody.
    Kreuzreaktivität (Details)
    Human.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Synthetic peptide corresponding to Type II Cytokeratins residues within aa300-400 of Type II Cytokeratins
    Isotyp
    IgG
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  • Applikationshinweise

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Positive_Control: Skin or squamous cell carcinoma.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    Cytokeratin 2 (KRT76) (Cytokeratin-2P (KRT76))
    Andere Bezeichnung
    KRT76 (KRT76 Produkte)
    Synonyme
    HUMCYT2A antikoerper, KRT2B antikoerper, KRT2P antikoerper, 2310001L23Rik antikoerper, keratin 76 antikoerper, KRT76 antikoerper, Krt76 antikoerper
    Hintergrund
    KRT2B, KRT2P, HUMCYT2A, Keratin, type II Cytoskeletal 2 oral, K76, Keratin 2p (K2P), Keratin-76, Cytokeratin-2P (CK-2P, Type-II Keratin Kb9,Cytokeratin, Type II (Epithelial Marker)
    Cellular localisation: Cytoplasmic
    Molekulargewicht
    66/65/64/57/62/60/51/54kDa
    Gen-ID
    51350, 654392
    UniProt
    Q01546
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