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Rekombinanter Bcl-2 Antikörper

BCL2 Reaktivität: Human WB, IHC, FACS, ELISA Wirt: Kaninchen Monoclonal 2C6 unconjugated Recombinant Antibody
Produktnummer ABIN7127273
  • Target Alle Bcl-2 (BCL2) Antikörper anzeigen
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 411
    • 170
    • 167
    • 34
    • 23
    • 22
    • 15
    • 10
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 321
    • 123
    • 5
    • 2
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 319
    • 134
    Monoklonal
    Konjugat
    • 200
    • 29
    • 27
    • 22
    • 20
    • 12
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Bcl-2 Antikörper ist unkonjugiert
    Applikation
    • 337
    • 184
    • 139
    • 107
    • 95
    • 93
    • 80
    • 65
    • 54
    • 30
    • 24
    • 24
    • 18
    • 8
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide
    Klon
    2C6
    Isotyp
    IgG
    Top Product
    Discover our top product BCL2 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Andere Bezeichnung
    BCL2 (BCL2 Produkte)
    Hintergrund

    Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).

    Aliases: Apoptosis regulator Bcl-2, BCL2

    UniProt
    P10415
    Pathways
    MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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