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Rekombinanter H2AFX Antikörper (pSer139)

H2AFX Reaktivität: Human WB, ELISA Wirt: Kaninchen Monoclonal 1F10 unconjugated Recombinant Antibody
Produktnummer ABIN7127309
  • Target Alle H2AFX Antikörper anzeigen
    H2AFX (H2A Histone Family, Member X (H2AFX))
    Antikörpertyp
    Recombinant Antibody
    Bindungsspezifität
    • 40
    • 26
    • 18
    • 11
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer139
    Reaktivität
    • 174
    • 90
    • 60
    • 26
    • 26
    • 20
    • 17
    • 12
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 147
    • 27
    • 2
    Kaninchen
    Klonalität
    • 127
    • 49
    Monoklonal
    Konjugat
    • 109
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser H2AFX Antikörper ist unkonjugiert
    Applikation
    • 134
    • 50
    • 46
    • 37
    • 33
    • 27
    • 22
    • 21
    • 16
    • 9
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide
    Klon
    1F10
    Isotyp
    IgG
    Top Product
    Discover our top product H2AFX Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:3000-1:10000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    H2AFX (H2A Histone Family, Member X (H2AFX))
    Andere Bezeichnung
    H2AFX (H2AFX Produkte)
    Synonyme
    H2A.X antikoerper, H2A/X antikoerper, H2AX antikoerper, AW228881 antikoerper, H2ax antikoerper, Hist5-2ax antikoerper, gammaH2ax antikoerper, zgc:56329 antikoerper, h2a.x antikoerper, h2a/x antikoerper, h2ax antikoerper, RGD1566119 antikoerper, h2a antikoerper, h2afx antikoerper, H2A histone family member X antikoerper, H2A histone family, member X antikoerper, H2A histone family member X L homeolog antikoerper, histone cluster 1, H2ah antikoerper, histone cluster 2, H2ab S homeolog antikoerper, histone H2AX antikoerper, H2AFX antikoerper, H2afx antikoerper, h2afx antikoerper, h2afx.L antikoerper, HIST1H2AH antikoerper, hist2h2ab.S antikoerper, LOC100522201 antikoerper, LOC100720536 antikoerper
    Hintergrund

    Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

    Aliases: Histone H2AX, H2a/x, Histone H2A.X, H2AFX, H2AX

    UniProt
    P16104
    Pathways
    Telomere Maintenance, DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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