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Rekombinanter Histone H3.3 Antikörper (pThr3)

H3F3A Reaktivität: Human ELISA, WB, FACS, ICC Wirt: Kaninchen Monoclonal 28H4 unconjugated Recombinant Antibody
Produktnummer ABIN7127311
  • Target Alle Histone H3.3 (H3F3A) Antikörper anzeigen
    Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
    Antikörpertyp
    Recombinant Antibody
    Bindungsspezifität
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    pThr3
    Reaktivität
    • 33
    • 4
    • 4
    • 1
    • 1
    • 1
    Human
    Wirt
    • 31
    • 3
    Kaninchen
    Klonalität
    • 27
    • 7
    Monoklonal
    Konjugat
    • 22
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Dieser Histone H3.3 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 17
    • 13
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide
    Klon
    28H4
    Isotyp
    IgG
    Top Product
    Discover our top product H3F3A Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, ICC:1:50-1:500,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
    Andere Bezeichnung
    H3F3A (H3F3A Produkte)
    Hintergrund

    Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Aliases: Histone H3.3, H3F3A, H3.3A, H3F3, PP781, AND, H3F3B, H3.3B

    UniProt
    P84243
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