Rekombinanter Histone H3.3 Antikörper (pThr3)
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- Target Alle Histone H3.3 (H3F3A) Antikörper anzeigen
- Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- pThr3
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser Histone H3.3 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide
- Klon
- 28H4
- Isotyp
- IgG
- Top Product
- Discover our top product H3F3A Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, ICC:1:50-1:500,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
- Andere Bezeichnung
- H3F3A (H3F3A Produkte)
- Hintergrund
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Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Aliases: Histone H3.3, H3F3A, H3.3A, H3F3, PP781, AND, H3F3B, H3.3B
- UniProt
- P84243
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