Rekombinanter APOC3 Antikörper
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- Target Alle APOC3 Antikörper anzeigen
- APOC3 (Apolipoprotein C-III (APOC3))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser APOC3 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human APOC3
- Klon
- 8H12
- Isotyp
- IgG
- Top Product
- Discover our top product APOC3 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- APOC3 (Apolipoprotein C-III (APOC3))
- Andere Bezeichnung
- APOC3 (APOC3 Produkte)
- Synonyme
- APOC3 antikoerper, APOCIII antikoerper, HALP2 antikoerper, Apoc antikoerper, ApoC-III antikoerper, apo-CIII antikoerper, Apo-CIII antikoerper, apolipoprotein C3 antikoerper, apolipoprotein C-III antikoerper, APOC3 antikoerper, Apoc3 antikoerper
- Hintergrund
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Background: Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806). Plays a multifaceted role in triglyceride homeostasis (PubMed:18201179, PubMed:22510806). Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion, extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs) (PubMed:18201179, PubMed:22510806). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors (PubMed:18201179, PubMed:22510806). Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners (PubMed:18408013).
Aliases: Apolipoprotein C-III (Apo-CIII) (ApoC-III) (Apolipoprotein C3), APOC3
- UniProt
- P02656
- Pathways
- Carbohydrate Homeostasis, Lipid Metabolism
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