Rekombinanter BAG3 Antikörper
Kurzübersicht für Rekombinanter BAG3 Antikörper (ABIN7127361)
Target
Alle BAG3 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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    - 
                                            Kreuzreaktivität
- Human
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                                            Aufreinigung
- Affinity-chromatography
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                                            Immunogen
- A synthesized peptide derived from human BAG3
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                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- -20 °C,-80 °C
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                                            Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - BAG3 (BCL2-Associated Athanogene 3 (BAG3))
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                                            Andere Bezeichnung
- BAG3
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                                            Hintergrund
- 
                        Background: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed:9873016, PubMed:27474739). Has anti-apoptotic activity (PubMed:10597216). Plays a role in the HSF1 nucleocytoplasmic transport (PubMed:26159920). Aliases: BAG family molecular chaperone regulator 3, BAG-3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, Docking protein CAIR-1, BAG3, BIS 
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                                            UniProt
- O95817
 Target
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