Rekombinanter BUB1B Antikörper
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- Target Alle BUB1B Antikörper anzeigen
- BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser BUB1B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human BubR1
- Klon
- 7H4
- Isotyp
- IgG
- Top Product
- Discover our top product BUB1B Primärantikörper
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anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) (AA 1-130) antibody
BUB1B Reaktivität: Human WB, ELISA, IHC (p), PLA, RNAi Wirt: Maus Monoclonal 2G5 unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) antibodyBUB1B Reaktivität: Human, Ratte, Affe, Hund WB, IF, FACS Wirt: Maus Monoclonal 6E3 unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) antibodyBUB1B Reaktivität: Human, Affe WB, IHC, IF, IHC (p) Wirt: Maus Monoclonal 11G2 unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) (AA 1-130) antibodyBUB1B Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 2G9 unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) (AA 230-394) antibodyBUB1B Reaktivität: Human IHC, ELISA, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) (C-Term) antibodyBUB1B Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) (AA 1-130) antibodyBUB1B Reaktivität: Human WB, IHC, ELISA, IHC (p), PLA, RNAi Wirt: Maus Monoclonal 2G5 unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) (AA 274-525) antibodyBUB1B Reaktivität: Human WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) antibodyBUB1B Reaktivität: Human, Maus WB, IF, IP, FACS, ICC Wirt: Maus Monoclonal 8G1 unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) (AA 751-850) antibodyBUB1B Reaktivität: Human, Maus WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, FC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))
- Andere Bezeichnung
- BUB1B (BUB1B Produkte)
- Hintergrund
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Background: Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE. Negatively regulates PLK1 activity in interphase cells and suppresses centrosome amplification. Also implicated in triggering apoptosis in polyploid cells that exit aberrantly from mitotic arrest. May play a role for tumor suppression.
Aliases: Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1), BUB1B, BUBR1 MAD3L SSK1
- UniProt
- O60566
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