Rekombinanter XPO1 Antikörper
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- Target Alle XPO1 Antikörper anzeigen
- XPO1 (Exportin 1 (XPO1))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser XPO1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human CRM1
- Klon
- 9F2
- Isotyp
- IgG
- Top Product
- Discover our top product XPO1 Primärantikörper
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anti-Exportin 1 (XPO1) (AA 966-1071) antibody
XPO1 Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 625-845) antibodyXPO1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 1 (XPO1) (C-Term) antibodyXPO1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio), Kaninchen, Schwein, Saccharomyces cerevisiae WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 1 (XPO1) antibodyXPO1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 817-846), (C-Term) antibodyXPO1 Reaktivität: Human IHC (p), FACS Wirt: Kaninchen Polyclonal RB19972 unconjugated
anti-Exportin 1 (XPO1) (acLys568) antibodyXPO1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 917-1071) antibodyXPO1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 1 (XPO1) (acLys568) antibodyXPO1 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 701-800) antibodyXPO1 Reaktivität: Human, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 2-122) antibodyXPO1 Reaktivität: Human, Maus, Ratte, Hund, Huhn WB, IF Wirt: Maus Monoclonal 17-Exportin unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- XPO1 (Exportin 1 (XPO1))
- Andere Bezeichnung
- XPO1 (XPO1 Produkte)
- Hintergrund
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Background: Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Involved in U3 snoRNA transport from Cajal bodies to nucleoli. Binds to late precursor U3 snoRNA bearing a TMG cap. Several viruses, among them HIV-1, HTLV-1 and influenza A use it to export their unspliced or incompletely spliced RNAs out of the nucleus. Interacts with, and mediates the nuclear export of HIV-1 Rev and HTLV-1 Rex proteins. Involved in HTLV-1 Rex multimerization.
Aliases: Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog), XPO1, CRM1
- UniProt
- O14980
- Pathways
- M Phase
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