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Rekombinanter E2F1 Antikörper

E2F1 Reaktivität: Human WB, ELISA, IHC, FACS, IF Wirt: Kaninchen Monoclonal 1D12 unconjugated Recombinant Antibody
Produktnummer ABIN7127462
  • Target Alle E2F1 Antikörper anzeigen
    E2F1 (E2F Transcription Factor 1 (E2F1))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 188
    • 90
    • 46
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Wirt
    • 190
    • 13
    • 2
    Kaninchen
    Klonalität
    • 181
    • 24
    Monoklonal
    Konjugat
    • 91
    • 15
    • 14
    • 11
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser E2F1 Antikörper ist unkonjugiert
    Applikation
    • 176
    • 87
    • 67
    • 66
    • 47
    • 30
    • 21
    • 19
    • 17
    • 17
    • 13
    • 13
    • 6
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Ratte
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human E2F1
    Klon
    1D12
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, FC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    E2F1 (E2F Transcription Factor 1 (E2F1))
    Andere Bezeichnung
    E2F1 (E2F1 Produkte)
    Hintergrund

    Background: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812).

    Aliases: Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1), E2F1, RBBP3

    UniProt
    Q01094
    Pathways
    p53 Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagie
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