Rekombinanter FAS Antikörper
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- Target Alle FAS Antikörper anzeigen
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser FAS Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human Fas
- Klon
- 2B6
- Isotyp
- IgG
- Top Product
- Discover our top product FAS Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- Andere Bezeichnung
- FAS (FAS Produkte)
- Hintergrund
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Background: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Aliases: Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95), FAS, APT1 FAS1 TNFRSF6
- UniProt
- P25445
- Pathways
- p53 Signalweg, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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